TY - JOUR ID - 124781 TI - An Interesting Similarity of Bacillus Calmette-Guerin and Chimeric Antigen Receptor T Cells JO - Translational Research in Urology JA - TRU LA - en SN - AU - Tamehri Zadeh, Seyed Saeed AU - Rezaeian, AhmadReza AD - Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran AD - Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Y1 - 2020 PY - 2020 VL - 2 IS - 3 SP - 107 EP - 109 KW - CAR-T cell KW - Bacillus Calmette-Guerin KW - Bladder Cancer Treatment DO - 10.22034/tru.2021.266267.1057 N2 - Intravesical Bacillus Calmette-Guerin (BCG) is approved for non-muscle invasive bladder cancer treatment a long time ago. Chimeric antigen receptor T cells (CAR-Tcell), are T cells are genetically engineered T cells that produce an artificial T-cell receptor for use in immunotherapy. Chimeric antigen receptors are receptor proteins that have been engineered to give T cells the new ability to target a specific protein Its effect is mostly achieved using activating the immune system; the same mechanism proposed likely for chimeric antigen receptor (CAR) T cells. Hence CAR-T cell therapy could be considered for bladder cancer treatment. UR - http://www.transresurology.com/article_124781.html L1 - http://www.transresurology.com/article_124781_43b0fda527966aff38446c893db0014e.pdf ER -