TY - JOUR ID - 125042 TI - Successful En-Bloc Kidney Transplantation from a 5-year-Old Donor with Cerebral Palsy to a 60-Year Old Recipient: A Case Report JO - Translational Research in Urology JA - TRU LA - en SN - AU - Khorrami, Mohammad Hatef AU - Dehghani, Sanaz AU - Mashhadi, Rahil AU - Abdi, Hossein AU - Namdari, Farshad AD - Isfahan University of Medical Sciences, Isfahan, Iran AD - Organ procurement unit of Sina hospital, Tehran University of Medical Sciences, Tehran, Iran AD - Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran AD - Aja university of medical sciences, Tehran, Iran Y1 - 2021 PY - 2021 VL - 3 IS - 1 SP - 19 EP - 22 KW - kidney transplant KW - pediatric donors KW - Organ donation KW - Circulatory Determination of Death DO - 10.22034/tru.2021.257484.1049 N2 - IntroductionThere are a growing number of unmet kidney donor sources. So, alternative donor sources, such as donation after circulatory determination of death (DCDD), are taken into the consideration.Case presentationIn this study, we represent successful En-Bloc kidney transplantation from a 4-year-Old donor with cerebral palsy to a 60-year old recipient. The kidney of a 4-year-old boy with congenital CP (weight=12Kg; BMI=12) with brain death was transplanted to a 60-year-old man (weight =70Kg; BMI=23.6). Panel-reactive antibody (PRA) to HLA class I (PRA I) and HLA class II (PRA II) were observed less than 5% in the 60-year old recipient. Also, the PRA titer with complement-dependent cytotoxicity (PRA-CDC) and the donor-recipient WBC crossmatch was negative. Our case is reported by a successful EKBT to an adult with the en-bloc kidney of a 4-year-old child with cerebral palsy. The small kidneys of a cerebral palsy child are adapting and functioning well in the adult body.ConclusionsTherefore, CP pediatric donors can be good resources for transplantation whenever available. UR - http://www.transresurology.com/article_125042.html L1 - http://www.transresurology.com/article_125042_54a43497f22e0695705cd3eaf79f94d1.pdf ER -