Document Type : Review
Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran
Isfahan Kidney Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
UroScience and Department of Surgery (Urology), School of Medical Sciences, University of Campinas, Unicamp, and Pontifical Catholic University of Campinas, PUC-Campinas, Campinas, S&amp;atilde;o Paulo, Brazil
Introduction and objectives: With the rapid worldwide spread of a new coronavirus with the scientific name SARS-CoV-2 at the beginning 2020, attempts to product a vaccine started in different countries. This study aimed to review mechanisms and functions of the coronavirus protein as a basis for vaccine production.
Methods: A rapid review on available studies is conducted. Related information was extracted and summarized, compared, and discussed with regards to the coronavirus mechanisms and acts as a pathogen, including apoptosis and autophagy.
Conclusion: An overview of available information on coronavirus functional mechanisms was performed to aid researchers in development and production of vaccines against it.
Apoptosis plays a significant role in the development of the pathogenesis of various cancers, autoimmune diseases, and viral infections. In addition, Autophagy is a main intracellular path for the damage and recycling of long-lived proteins and damaged organelles.