%0 Journal Article %T An Interesting Similarity of Bacillus Calmette-Guerin and Chimeric Antigen Receptor T Cells %J Translational Research in Urology %I Urology Research Center, Tehran University of Medical Sciences %Z 2717-042X %A Tamehri Zadeh, Seyed Saeed %A Rezaeian, AhmadReza %D 2020 %\ 08/15/2020 %V 2 %N 3 %P 107-109 %! An Interesting Similarity of Bacillus Calmette-Guerin and Chimeric Antigen Receptor T Cells %K CAR-T cell %K Bacillus Calmette-Guerin %K Bladder Cancer Treatment %R 10.22034/tru.2021.266267.1057 %X Intravesical Bacillus Calmette-Guerin (BCG) is approved for non-muscle invasive bladder cancer treatment a long time ago. Chimeric antigen receptor T cells (CAR-Tcell), are T cells are genetically engineered T cells that produce an artificial T-cell receptor for use in immunotherapy. Chimeric antigen receptors are receptor proteins that have been engineered to give T cells the new ability to target a specific protein Its effect is mostly achieved using activating the immune system; the same mechanism proposed likely for chimeric antigen receptor (CAR) T cells. Hence CAR-T cell therapy could be considered for bladder cancer treatment. %U http://www.transresurology.com/article_124781_43b0fda527966aff38446c893db0014e.pdf